17th EPI Program

Wednesday 5th



13:30-15:00
Registration
15:00-15:15
Opening ceremony
Session 1. Chairpersons: Ernest Giralt, David Pantoja-Uceda
GERMN-sponsored Lectures
15:15-16:05 PL1 Anna Maria Papini . University of Firenze, Italy

Strategies for modulation of secondary structures to optimise biological recognition
16:05-16:35 KN1 Douglas V. Laurents. IQFR-CSIC. Madrid, Spain

Structures and Applications of Antifreeze Polypeptides
16:35-17:05 Coffee Break
Session 2. Chairpersons: Joao D. G. Correia, May C. Morris
17:05-17:20 OC1 María Abad. Vall d'Hebron Institute of Oncology-VHIO, Barcelona, Spain

When the non-coding codes: Mining the Microproteome for New Players in Cancer Cell Plasticity
17:20-17:35 OC2 Isidra Recio. CIAL-CSIC. Madrid, Spain

Release of anorexigenic hormones induced by in vivo and in vitro gastrointestinal digests of milk proteins. Peptides involved in hormone secretion
17:35-17:50 OC3 María Gallo. University Pompeu Fabra. Barcelona, Spain

A BBB-crossing peptide vector allows using cannabis to fight pain while avoiding side effects
17:50-18:05 OC4 Salvador Guardiola. IRB. Barcelona, Spain

Peptides and nanobodies as EGF-EGFR inhibitors: towards a new class of drugs?
18:05-18:20 OC5 Alicia Boto. IPNA-CSIC. La Laguna, Tenerife, Spain

Site-selective modification of peptides in antimicrobial discovery for health and agriculture
18:20-18:35 OC6 Ana Gomes. University of Porto, Portugal

Peptide chimeras for skin infection with collagen-boosting effect, antibacterial and antibiofilm activity
18:35-18:40 SC1 Jorge Losada Méndez. Instituto de Investigaciones Químicas (IIQ-CSIC), Sevilla, Spain

Peptides conjugated to synthetic agonists of Toll-like receptors as potential vaccines in immunotherapy
18:40-18:45 SC2 Iara Mota-Silva. Instituto de Medicina Molecular. Lisboa, Portugal

Neuropeptide Kyotorphin impact on diabetic retinopathy and its correlation with diabetes mellitus derived inflammation
18:45-18:50 SC3 Marta Varela-Eirín. Instituto de Investigación Biomédica de A Coruña (INIBIC). Spain

The senolytic activity of peptides of the C-terminal domain of Cx43 target senescence in osteoarthritis
18:50-18:55 SC4 Cátia Teixeira. University of Porto, Portugal

Repurposing known antimicrobial peptides to combat phytopathogenic agents
19:30 Welcome cocktail

Thursday 6th

Session 3. Chairpersons: Nuno Santos, Mª Jesús Pérez de Vega
9:00-9:30 KN2 Cristina L. Martins. University of Porto, Portugal

Impact of surface conjugation on the bactericidal activity of antimicrobial peptides
09:30-09:45 OC7 Esperanza Rivera-de-Torre. UCM. Madrid, Spain

Structural and functional characterization of Latrodectins I and II, low molecular weight peptidic components from Latrodectus hesperus venom
09:45-10:00 OC8 Francisco J. Blanco. CIC bioGUNE. Bilbao, Spain

Double monoubiquitination of the IDP p15 promotes binding to Dnmt1
10:00-10:15 OC9 Geert A. Daudey. University of Santiago de Compostela, Spain

pH Responsive coiled coil peptides with tunable membrane disruption
10:15-10:30 OC10 Miguel Mompeán. IQFR-CSIC. Madrid, Spain

The homo- and hetero-oligomeric foldomes of functional and pathological amyloids
10:30-10:35 SC5 Mónica Aróstica.Catholic University of Valparaiso/USM, Chile

Comparative study of structure/antibacterial function of the short peptide derived from Rainbow trout cathelicidin and its oxidized form
10:35-10:40 SC6 Christine Cruz-Oliveira. Instituto de Medicina Molecular João Lobo Antunes, Lisboa, Portugal

Fighting central nervous system arboviral infections with peptide/ porphyrin-based conjugates
10:40-10:45 SC7 David Bouzada. CIQUS, Universidad de Santiago de Compostela

Use of a self-assembling protein for the nucleation of gold nanoclusters
10:45-11:15 Coffee break
Session 4. Chairpersons: Meritxell Teixidó, Jerónimo Bravo
11:15-11:30 OC11 Alejandro Revuelto. IQM-CSIC. Madrid, Spain

Potent small molecule dimerization disruptors of Trypanothione reductase with antileishmanial activity and improved selectivity
11:30-11:45 OC12 José Manuel Pérez de la Lastra. IPNA-CSIC. La Laguna, Tenerife, Spain

Antifungal activity of two cathelicidins against Botrytis cinerea. Applications to Agriculture
11:45-12:00 OC13 Mar Forner. UPF. Barcelona, Spain

Insights into B2T synthetic vaccine constructs: structural studies and click chemistry for tail-to-tail fusion
12:00-12:15 OC14 João Correia. Instituto Superior Técnico, Universidade de Lisboa, Portugal

Ruthenium-peptide conjugates for the selective treatment of triple-negative breast cancer
12:15-12:30 OC15 Fernando Montero Segovia. University of Granada, Spain

Peptide binding of the UEV domain of TSG101 protein
12:30-12:45 OC16 Mariana Damián. BIOTAGE, Madrid, Spain

Biotage: your peptide partner
12:45-12:50 SC8 Clara Pérez-Peinado. UPF. Barcelona, Spain

Crotalicidin (Ctn) and its Ctn[15-34] fragment: insights into their proteolytic sensitivity and antitumoral mechanism
12:50-12:55 SC9 Ana Rita Ferreira. University of Porto, Portugal

What happens to the antimicrobial and membrane activity upon adding an N-terminal tryptophan to a cecropin-melittin inspired peptide?
12:55-13:00 SC10 Rúben D. M. Silva. Instituto Superior Técnico. Lisboa, Portugal

Thermally-induced denaturation of ß-sheet structure of polyglutamine
13:00-15:00 Lunch
Session 5. Chairpersons: Isidra Recio, Jesús M. Sanz
15:00-15:30 KN3 Fidel Toldrá. CSIC, Valencia, Spain

Bioactive peptides in processed foods and its relevance for health
15:30-15:45 OC17 Guillermo Santos-Sánchez. IBiS, Sevilla, Spain

Lupine protein hydrolysates: how their lipid-lowering, antioxidant and anti-inflammatory effects favour an antiatherogenic environment in Apoe-/-mice.
15:45-16:00 OC18 May C. Morris. Institut des Biomolécules Max Mousseron. Montpellier, France

Stapled peptide targeting the CDK4/cyclin D interface synergizes with Abemaciclib to inhibit proliferation of non-small cell lung cancer cells and tumours
16:00-16:15 OC19 Luísa Aguiar. University of Porto, Portugal

Can cell penetrating peptides efficiently deliver the antimalarial drug chloroquine to infected red blood cells?
16:15-16:30 OC20 Nicanor Zalba. CIC bioGUNE. Bilbao, Spain

The effect of cosolutes in biomolecular stability as investigated by NMR spectroscopy.
16:30-16:35 SC11 Federica Nicolini. IRB. Barcelona, Spain

Design of peptides able to modulate Protein-Protein Interactions (PPIs)
16:35-16:40 SC12 Beatriz Miralles. CIAL-CSIC. Madrid, Spain

Novel opioid activity of milk casein-derived fragments: structure-activity relationship
16:40-16:45 SC13 Mónica Varese. IRB. Barcelona, Spain

Modulation of therapeutically relevant protein-protein interactions by photoswitchable peptides
16:45-16:50 SC14 Stephen J. Barigye. PROTOQSAR SL. Valencia, Spain

PeptiDesCalculator : Novel Software for Computation of Theoretical Peptide Descriptors
16:50-17:15 Coffee Break
17:15-18:00
Poster's Session.
Session 6. Chairpersons: Alicia Boto, Marta Gutiérrez
18:00-18:15 OC21 Jerónimo Bravo. IBV-CSIC. Valencia, Spain

Peptides against the ribosome biogenesis complex Bop1/WDR12
18:15-18:30 OC22 Mercedes Martin-Martínez. IQM-CSIC. Madrid, Spain

Insights into synaptotagmin-1 C2B domain as a putative target for new analgesics
18:30-18:45 OC23 Salvatore Di Maro. University of Campania "Luigi Vanvitelli". Caserta, Italy

Ultrasonic Fmoc-Solid Phase Peptide Synthesis (US-SPPS)
18:45-19:00 OC24 Carles Mas-Moruno. Politechnic University of Catalunya. Barcelona, Spain

Mimicking the extracellular matrix with peptides: tailoring tissue regeneration
21:00 Gala Dinner

Friday 7th

Session 7. Chairpersons: Federico Gago, Francisco Blanco
09:30-10:00 KN4 Manuel N. Melo. Universidade Nova de Lisboa, Portugal

Peptides, pores, and cool ways to simulate them
10:00-10:15 OC25 Víctor A. Lorenz-Fonfria. University of Valencia, Spain

Ultra-slow refolding dynamics of a photoswitchable hydrophobic helical peptide in lipidic membranes
10:15-10:30 OC26 Xavier Just-Baringo. IRB. Barcelona, Spain

Solid Phase Synthesis of Visible Light Active Photoswitchable Antibiotics
10:30-10:45 OC27 Marco Cavaco. Instituto de Medicina Molecular. Lisboa, Portugal

A methodology to predict peptide stability based on chemical properties
10:45-11:00 OC28 Toni Todorovski. UPF. Barcelona, Spain

Development of new ZIKV-active porphyrin-peptide conjugates
11:00-11:30 Coffee break
Session 8. Chairpersons: Paula Gomes, Carles Mas-Moruno
11:30-11:45 OC29 Jesús M. Sanz. CIB-CSIC. Madrid, Spain

Synthetic choline binding repeats as antimicrobial switch peptides
11:45-12:00 OC30 Steffano Tomassi. University of Naples, Italy

Mimicking disulfide bridge with 1,4- and 1,5-disubstituted 1,2,3-triazole: a case study on CXCR4
12:00-12:15 OC31 Salvador Ventura. UAB. Barcelona, Spain

Minimalist Prion-Inspired Polar Self-Assembling Peptides
12:15-12:30 OC32 Bartolomé Vilanova. University of Balearic Islands. Palma de Mallorca, Spain

Effect of some metal ions on the fibril formation process of wild type and post-translational modified alpha-synuclein
12:30-13:20 Molecules-sponsored Lecture
PL2 Ian W Hamley . University of Reading, UK

Bioactive Self-Assembling Peptides and Lipopeptides
13:20-13:30
Best Oral Communication Awards + Closing Remarks
13:30-15:30 Lunch